B1-cell-produced anti-phosphatidylserine antibodies contribute to lupus nephritis development via TLR-mediated Syk activation

Autoantibodies produced by B cells play a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). However, both the cellular source of antiphospholipid antibodies and their contributions to the development of lupus nephritis (LN) remain largely unclear. Here, we report a pathogenic r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Kongyang, Du, Wenhan, Wang, Shiyun, Xiao, Fan, Li, Jingyi, Tian, Jie, Xing, Yida, Kong, Xiaodan, Rui, Ke, Qin, Rencai, Zhu, Xiaoxia, Wang, Jing, Luo, Cainan, Wu, Haijing, Zhang, Yun, Wen, Chengping, He, Lan, Liu, Dongzhou, Zou, Hejian, Lu, Qianjin, Wu, Lijun, Lu, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250184/
https://www.ncbi.nlm.nih.gov/pubmed/37291237
http://dx.doi.org/10.1038/s41423-023-01049-2

Ejemplares similares

Ejemplares similares