CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension

CST (CTC1-STN1-TEN1) is a telomere associated complex that binds ssDNA and is required for multiple steps in telomere replication, including termination of G-strand extension by telomerase and synthesis of the complementary C-strand. CST contains seven OB-folds which appear to mediate CST function b...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Ma, Tengfei, Zhang, Xiaotong, Chen, Wei, Lan, Yina, Kuang, Guotao, Hsu, Shih-Jui, He, Zibin, Chen, Yuxi, Stewart, Jason, Bhattacharjee, Anukana, Luo, Zhenhua, Price, Carolyn, Feng, Xuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250220/
https://www.ncbi.nlm.nih.gov/pubmed/37021555
http://dx.doi.org/10.1093/nar/gkad237

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