Zinc cluster transcription factors frequently activate target genes using a non-canonical half-site binding mode

Gene expression changes are orchestrated by transcription factors (TFs), which bind to DNA to regulate gene expression. It remains surprisingly difficult to predict basic features of the transcriptional process, including in vivo TF occupancy. Existing thermodynamic models of TF function are often n...

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Detalles Bibliográficos
Autores principales: Recio, Pamela S, Mitra, Nikhil J, Shively, Christian A, Song, David, Jaramillo, Grace, Lewis, Kristine Shady, Chen, Xuhua, Mitra, Robi D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250231/
https://www.ncbi.nlm.nih.gov/pubmed/37125648
http://dx.doi.org/10.1093/nar/gkad320

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