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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs

Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major clinical trials in patients with reperfused acute myocardial infarction were equivocal. We, therefore, went back and tested the translational robustne...

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Detalles Bibliográficos
Autores principales: Kleinbongard, Petra, Lieder, Helmut Raphael, Skyschally, Andreas, Heusch, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250284/
https://www.ncbi.nlm.nih.gov/pubmed/37289247
http://dx.doi.org/10.1007/s00395-023-00993-4