Cargando…
Buckling critical pressures in collapsible tubes relevant for biomedical flows
The behaviour of collapsed or stenotic vessels in the human body can be studied by means of simplified geometries like a collapsible tube. The objective of this work is to determine the value of the buckling critical pressure of a collapsible tube by employing Landau’s theory of phase transition. Th...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250313/ https://www.ncbi.nlm.nih.gov/pubmed/37291334 http://dx.doi.org/10.1038/s41598-023-36513-6 |
_version_ | 1785055729300799488 |
---|---|
author | Laudato, Marco Mosca, Roberto Mihaescu, Mihai |
author_facet | Laudato, Marco Mosca, Roberto Mihaescu, Mihai |
author_sort | Laudato, Marco |
collection | PubMed |
description | The behaviour of collapsed or stenotic vessels in the human body can be studied by means of simplified geometries like a collapsible tube. The objective of this work is to determine the value of the buckling critical pressure of a collapsible tube by employing Landau’s theory of phase transition. The methodology is based on the implementation of an experimentally validated 3D numerical model of a collapsible tube. The buckling critical pressure is estimated for different values of geometric parameters of the system by treating the relation between the intramural pressure and the area of the central cross-section as the order parameter function of the system. The results show the dependence of the buckling critical pressures on the geometric parameters of a collapsible tube. General non-dimensional equations for the buckling critical pressures are derived. The advantage of this method is that it does not require any geometric assumption, but it is solely based on the observation that the buckling of a collapsible tube can be treated as a second-order phase transition. The investigated geometric and elastic parameters are sensible for biomedical application, with particular interest to the study of the bronchial tree under pathophysiological conditions like asthma. |
format | Online Article Text |
id | pubmed-10250313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-102503132023-06-10 Buckling critical pressures in collapsible tubes relevant for biomedical flows Laudato, Marco Mosca, Roberto Mihaescu, Mihai Sci Rep Article The behaviour of collapsed or stenotic vessels in the human body can be studied by means of simplified geometries like a collapsible tube. The objective of this work is to determine the value of the buckling critical pressure of a collapsible tube by employing Landau’s theory of phase transition. The methodology is based on the implementation of an experimentally validated 3D numerical model of a collapsible tube. The buckling critical pressure is estimated for different values of geometric parameters of the system by treating the relation between the intramural pressure and the area of the central cross-section as the order parameter function of the system. The results show the dependence of the buckling critical pressures on the geometric parameters of a collapsible tube. General non-dimensional equations for the buckling critical pressures are derived. The advantage of this method is that it does not require any geometric assumption, but it is solely based on the observation that the buckling of a collapsible tube can be treated as a second-order phase transition. The investigated geometric and elastic parameters are sensible for biomedical application, with particular interest to the study of the bronchial tree under pathophysiological conditions like asthma. Nature Publishing Group UK 2023-06-08 /pmc/articles/PMC10250313/ /pubmed/37291334 http://dx.doi.org/10.1038/s41598-023-36513-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Laudato, Marco Mosca, Roberto Mihaescu, Mihai Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title | Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title_full | Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title_fullStr | Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title_full_unstemmed | Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title_short | Buckling critical pressures in collapsible tubes relevant for biomedical flows |
title_sort | buckling critical pressures in collapsible tubes relevant for biomedical flows |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250313/ https://www.ncbi.nlm.nih.gov/pubmed/37291334 http://dx.doi.org/10.1038/s41598-023-36513-6 |
work_keys_str_mv | AT laudatomarco bucklingcriticalpressuresincollapsibletubesrelevantforbiomedicalflows AT moscaroberto bucklingcriticalpressuresincollapsibletubesrelevantforbiomedicalflows AT mihaescumihai bucklingcriticalpressuresincollapsibletubesrelevantforbiomedicalflows |