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Investigating the novel-binding site of RPA2 on Menin and predicting the effect of point mutation of Menin through protein–protein interactions

Protein–protein interactions (PPIs) play a critical role in all biological processes. Menin is tumor suppressor protein, mutated in multiple endocrine neoplasia type 1 syndrome and has been shown to interact with multiple transcription factors including (RPA2) subunit of replication protein A (RPA)....

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Detalles Bibliográficos
Autores principales: Kaur, Gurjeet, Prajapat, Manisha, Singh, Harvinder, sarma, Phulen, Bhadada, Sanjay kumar, Shekhar, Nishant, Sharma, Saurabh, Sinha, Shweta, kumar, Subodh, Prakash, Ajay, Medhi, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250348/
https://www.ncbi.nlm.nih.gov/pubmed/37291166
http://dx.doi.org/10.1038/s41598-023-35599-2