Cargando…
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and considerable off-target expression of the potentially targ...
Autores principales: | Mensali, Nadia, Köksal, Hakan, Joaquina, Sandy, Wernhoff, Patrik, Casey, Nicholas P., Romecin, Paola, Panisello, Carla, Rodriguez, René, Vimeux, Lene, Juzeniene, Asta, Myhre, Marit R., Fåne, Anne, Ramírez, Carolina Castilla, Maggadottir, Solrun Melkorka, Duru, Adil Doganay, Georgoudaki, Anna-Maria, Grad, Iwona, Maturana, Andrés Daniel, Gaudernack, Gustav, Kvalheim, Gunnar, Carcaboso, Angel M., de Alava, Enrique, Donnadieu, Emmanuel, Bruland, Øyvind S., Menendez, Pablo, Inderberg, Else Marit, Wälchli, Sébastien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250459/ https://www.ncbi.nlm.nih.gov/pubmed/37291203 http://dx.doi.org/10.1038/s41467-023-39097-x |
Ejemplares similares
-
A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT)
por: Maggadóttir, Sólrún Melkorka, et al.
Publicado: (2022) -
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
por: Dillard, Pierre, et al.
Publicado: (2021) -
Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
por: Mensali, Nadia, et al.
Publicado: (2019) -
Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
por: Mensali, Nadia, et al.
Publicado: (2019) -
NK cells specifically TCR-dressed to kill cancer cells
por: Mensali, Nadia, et al.
Publicado: (2019)