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Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study

Coronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we aimed to disclose the characteristics of athe...

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Autores principales: Yu, Huai, Dai, Jiannan, Tang, Hao, Fang, Chao, Jiang, Senqing, Xu, Xueming, Yu, Bo, Tu, Yingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250510/
https://www.ncbi.nlm.nih.gov/pubmed/37099062
http://dx.doi.org/10.1007/s10554-023-02835-9
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author Yu, Huai
Dai, Jiannan
Tang, Hao
Fang, Chao
Jiang, Senqing
Xu, Xueming
Yu, Bo
Tu, Yingfeng
author_facet Yu, Huai
Dai, Jiannan
Tang, Hao
Fang, Chao
Jiang, Senqing
Xu, Xueming
Yu, Bo
Tu, Yingfeng
author_sort Yu, Huai
collection PubMed
description Coronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we aimed to disclose the characteristics of atherosclerotic plaques in patients with CAE using optical coherence tomography (OCT). We evaluated patients with CAE, confirmed by coronary angiography, who underwent pre-intervention OCT between April 2015 and April 2021. Each millimeter of the OCT images was analyzed to assess the characteristics of CAEs, plaque phenotypes, and plaque vulnerability. A total of 286 patients (344 coronary vessels) met our criteria, 82.87% of whom were men. Right coronary artery lesions were the most common, comprising 44.48% (n = 153) of the total. We found 329 CAE vessels with plaques, accounting for 95.64% of the coronary vessels. After grouping CAEs and plaques by their relative positions, we found that the length of plaques within CAE lesions was longer than that of plaques in other sites (P < 0.001). Plaques within CAE lesions had greater maximum lipid angles and lipid indexes (P = 0.007, P = 0.004, respectively) than those on other sites. This study revealed the most common vascular and morphological characteristics of CAE. While the accompanying plaques were not affected by the location or morphology of the CAE vessels, they were affected by their position relative to the CAE lesion. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10554-023-02835-9.
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spelling pubmed-102505102023-06-10 Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study Yu, Huai Dai, Jiannan Tang, Hao Fang, Chao Jiang, Senqing Xu, Xueming Yu, Bo Tu, Yingfeng Int J Cardiovasc Imaging Research Article Coronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we aimed to disclose the characteristics of atherosclerotic plaques in patients with CAE using optical coherence tomography (OCT). We evaluated patients with CAE, confirmed by coronary angiography, who underwent pre-intervention OCT between April 2015 and April 2021. Each millimeter of the OCT images was analyzed to assess the characteristics of CAEs, plaque phenotypes, and plaque vulnerability. A total of 286 patients (344 coronary vessels) met our criteria, 82.87% of whom were men. Right coronary artery lesions were the most common, comprising 44.48% (n = 153) of the total. We found 329 CAE vessels with plaques, accounting for 95.64% of the coronary vessels. After grouping CAEs and plaques by their relative positions, we found that the length of plaques within CAE lesions was longer than that of plaques in other sites (P < 0.001). Plaques within CAE lesions had greater maximum lipid angles and lipid indexes (P = 0.007, P = 0.004, respectively) than those on other sites. This study revealed the most common vascular and morphological characteristics of CAE. While the accompanying plaques were not affected by the location or morphology of the CAE vessels, they were affected by their position relative to the CAE lesion. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10554-023-02835-9. Springer Netherlands 2023-04-26 2023 /pmc/articles/PMC10250510/ /pubmed/37099062 http://dx.doi.org/10.1007/s10554-023-02835-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Yu, Huai
Dai, Jiannan
Tang, Hao
Fang, Chao
Jiang, Senqing
Xu, Xueming
Yu, Bo
Tu, Yingfeng
Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title_full Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title_fullStr Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title_full_unstemmed Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title_short Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
title_sort characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250510/
https://www.ncbi.nlm.nih.gov/pubmed/37099062
http://dx.doi.org/10.1007/s10554-023-02835-9
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