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Sex‐specific repolarization heterogeneity in mouse left ventricle: Optical mapping combined with mathematical modeling predict the contribution of specific ionic currents

Ventricular repolarization shows notable sex‐specificity, with female sex being associated with longer QT‐intervals in electrocardiography irrespective of the species studied. From a clinical point of view, women are at a greater risk for drug‐induced torsade de pointes and symptomatic long‐QT syndr...

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Detalles Bibliográficos
Autores principales: Moussavi‐Torshizi, S. Erfan, Amin, Ehsan, Klöcker, Nikolaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250535/
https://www.ncbi.nlm.nih.gov/pubmed/37291479
http://dx.doi.org/10.14814/phy2.15670