Tumour mutations in long noncoding RNAs enhance cell fitness

Long noncoding RNAs (lncRNAs) are linked to cancer via pathogenic changes in their expression levels. Yet, it remains unclear whether lncRNAs can also impact tumour cell fitness via function-altering somatic “driver” mutations. To search for such driver-lncRNAs, we here perform a genome-wide analysi...

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Detalles Bibliográficos
Autores principales: Esposito, Roberta, Lanzós, Andrés, Uroda, Tina, Ramnarayanan, Sunandini, Büchi, Isabel, Polidori, Taisia, Guillen-Ramirez, Hugo, Mihaljevic, Ante, Merlin, Bernard Mefi, Mela, Lia, Zoni, Eugenio, Hovhannisyan, Lusine, McCluggage, Finn, Medo, Matúš, Basile, Giulia, Meise, Dominik F., Zwyssig, Sandra, Wenger, Corina, Schwarz, Kyriakos, Vancura, Adrienne, Bosch-Guiteras, Núria, Andrades, Álvaro, Tham, Ai Ming, Roemmele, Michaela, Medina, Pedro P., Ochsenbein, Adrian F., Riether, Carsten, Kruithof-de Julio, Marianna, Zimmer, Yitzhak, Medová, Michaela, Stroka, Deborah, Fox, Archa, Johnson, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250536/
https://www.ncbi.nlm.nih.gov/pubmed/37291246
http://dx.doi.org/10.1038/s41467-023-39160-7

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