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Sex and gender influence on immunity and autoimmunity

Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.

Detalles Bibliográficos
Autor principal: Lahita, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250588/
https://www.ncbi.nlm.nih.gov/pubmed/37304263
http://dx.doi.org/10.3389/fimmu.2023.1142723
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author Lahita, Robert G.
author_facet Lahita, Robert G.
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description Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.
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spelling pubmed-102505882023-06-10 Sex and gender influence on immunity and autoimmunity Lahita, Robert G. Front Immunol Immunology Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors. Frontiers Media S.A. 2023-05-26 /pmc/articles/PMC10250588/ /pubmed/37304263 http://dx.doi.org/10.3389/fimmu.2023.1142723 Text en Copyright © 2023 Lahita https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Lahita, Robert G.
Sex and gender influence on immunity and autoimmunity
title Sex and gender influence on immunity and autoimmunity
title_full Sex and gender influence on immunity and autoimmunity
title_fullStr Sex and gender influence on immunity and autoimmunity
title_full_unstemmed Sex and gender influence on immunity and autoimmunity
title_short Sex and gender influence on immunity and autoimmunity
title_sort sex and gender influence on immunity and autoimmunity
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250588/
https://www.ncbi.nlm.nih.gov/pubmed/37304263
http://dx.doi.org/10.3389/fimmu.2023.1142723
work_keys_str_mv AT lahitarobertg sexandgenderinfluenceonimmunityandautoimmunity