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The macrophage infectivity potentiator of Trypanosoma cruzi induces innate IFN-γ and TNF-α production by human neonatal and adult blood cells through TLR2/1 and TLR4

We previously identified the recombinant (r) macrophage (M) infectivity (I) potentiator (P) of the protozoan parasite Trypanosoma cruzi (Tc) (rTcMIP) as an immuno-stimulatory protein that induces the release of IFN-γ, CCL2 and CCL3 by human cord blood cells. These cytokines and chemokines are import...

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Detalles Bibliográficos
Autores principales: Ait Djebbara, Sarra, Mcheik, Saria, Percier, Pauline, Segueni, Noria, Poncelet, Antoine, Truyens, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250606/
https://www.ncbi.nlm.nih.gov/pubmed/37304288
http://dx.doi.org/10.3389/fimmu.2023.1180900

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