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Apolipoprotein E intersects with amyloid-β within neurons

Apolipoprotein E4 (ApoE4) is the most important genetic risk factor for Alzheimer’s disease (AD). Among the earliest changes in AD is endosomal enlargement in neurons, which was reported as enhanced in ApoE4 carriers. ApoE is thought to be internalized into endosomes of neurons, whereas β-amyloid (A...

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Detalles Bibliográficos
Autores principales:	Konings, Sabine C, Nyberg, Emma, Martinsson, Isak, Torres-Garcia, Laura, Klementieva, Oxana, Guimas Almeida, Claudia, Gouras, Gunnar K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250689/ https://www.ncbi.nlm.nih.gov/pubmed/37290814 http://dx.doi.org/10.26508/lsa.202201887

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