Tfl deletion induces extraordinary Cxcl13 secretion and cachexia in VavP-Bcl2 transgenic mice

Statement of significance: Loss of TFL, found in several types of lymphoma, induces excessive CXCL13 secretion through RNA dysregulation contributing to body weight loss and early death in lymphoma model mice. Follicular lymphoma (FL) is associated with overexpressed BCL-2 and other genetic aberrati...

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Detalles Bibliográficos
Autores principales: Minagawa, Kentaro, Wakahashi, Kanako, Fukui, Chie, Kawano, Yuko, Kawano, Hiroki, Suzuki, Tomohide, Ishii, Shinichi, Sada, Akiko, Nishikawa, Shinichiro, Asada, Noboru, Katayama, Yoshio, Matsui, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250710/
https://www.ncbi.nlm.nih.gov/pubmed/37304286
http://dx.doi.org/10.3389/fimmu.2023.1197112

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