Metformin attenuates diabetes-induced osteopenia in rats is associated with down-regulation of the RAGE-JAK2-STAT1 signal axis

BACKGROUND: Osteopenia and fragile fractures are diabetes-associated complications. Many hypoglycemic drugs have effects on bone metabolism. Metformin, as is a prescribed medication for type 2 diabetes mellitus (T2DM), had been reported to have osteoprotective effects beyond its hypoglycemic effect,...

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Detalles Bibliográficos
Autores principales: Lin, Rui, Xu, Bilian, Ye, Zhiqiang, Gao, Yin, Fang, Haiping, Song, Jintong, Liang, Dahong, Liu, Lingna, Hu, Zilong, Zhang, Min, Wei, Jinsong, Deng, Feifu, Zhong, Xiangxin, Cui, Liao, Liu, Yanzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250823/
https://www.ncbi.nlm.nih.gov/pubmed/37304218
http://dx.doi.org/10.1016/j.jot.2023.05.002

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