Cargando…

Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been demonstrated to play a critical role in regulating cholesterol homeostasis and T cell antitumor immunity. However, the expression, function, and therapeutic value of PCSK9 in head and neck squamous cell carcinoma (HNSCC) remain largely u...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qi-Chao, Wang, Shuo, Liu, Yuan-Tong, Song, An, Wu, Zhi-Zhong, Wan, Shu-Cheng, Li, Hui-Min, Sun, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250824/
https://www.ncbi.nlm.nih.gov/pubmed/37305703
http://dx.doi.org/10.1016/j.isci.2023.106916