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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been demonstrated to play a critical role in regulating cholesterol homeostasis and T cell antitumor immunity. However, the expression, function, and therapeutic value of PCSK9 in head and neck squamous cell carcinoma (HNSCC) remain largely u...
Autores principales: | Yang, Qi-Chao, Wang, Shuo, Liu, Yuan-Tong, Song, An, Wu, Zhi-Zhong, Wan, Shu-Cheng, Li, Hui-Min, Sun, Zhi-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250824/ https://www.ncbi.nlm.nih.gov/pubmed/37305703 http://dx.doi.org/10.1016/j.isci.2023.106916 |
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