Rational design, synthesis and structural characterization of peptides and peptidomimetics to target Hsp90/Cdc37 interaction for treating hepatocellular carcinoma

Heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) work together as a molecular chaperone complex to regulate the activity of a multitude of client protein kinases. These kinases belong to a wide array of intracellular signaling networks that mediate multiple cellular processes includi...

Descripción completa

Detalles Bibliográficos
Autores principales: Sukumaran, Surya, Tan, Mingdian, Ben-Uliel, Shulamit Fluss, Zhang, Hui, De Zotti, Marta, Chua, Mei-Sze, So, Samuel K., Qvit, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250827/
https://www.ncbi.nlm.nih.gov/pubmed/37304004
http://dx.doi.org/10.1016/j.csbj.2023.05.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250827/
https://www.ncbi.nlm.nih.gov/pubmed/37304004
http://dx.doi.org/10.1016/j.csbj.2023.05.023

Ejemplares similares