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Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A
Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it mediates Na(+)-dependent uptake of ω−3 fatty acids in the form of lysolipids into the brain and eyes, respectively. Despite recent structural...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250862/ https://www.ncbi.nlm.nih.gov/pubmed/37296098 http://dx.doi.org/10.1038/s41467-023-39088-y |