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Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A

Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it mediates Na(+)-dependent uptake of ω−3 fatty acids in the form of lysolipids into the brain and eyes, respectively. Despite recent structural...

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Detalles Bibliográficos
Autores principales:	Bergman, Shana, Cater, Rosemary J., Plante, Ambrose, Mancia, Filippo, Khelashvili, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250862/ https://www.ncbi.nlm.nih.gov/pubmed/37296098 http://dx.doi.org/10.1038/s41467-023-39088-y

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