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Combination of IDO inhibitors and platinum(IV) prodrugs reverses low immune responses to enhance cancer chemotherapy and immunotherapy for osteosarcoma

In recent years, immune checkpoint blockades (ICBs) have made great progress in the treatment of cancer. However, most ICBs have not yet been observed to be satisfactory in the treatment of osteosarcoma. Herein, we designed composite nanoparticles (NP–Pt-IDOi) from a reactive oxygen species (ROS) se...

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Detalles Bibliográficos
Autores principales: Xiang, Dongquan, Han, Xinli, Li, Jianxiong, Zhang, Jiabing, Xiao, Haihua, Li, Ting, Zhao, Xuelin, Xiong, Hejian, Xu, Meng, Bi, Wenzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250924/
https://www.ncbi.nlm.nih.gov/pubmed/37304579
http://dx.doi.org/10.1016/j.mtbio.2023.100675