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Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions
Both deterministic and stochastic forces shape biofilm communities, but the balance between those forces is variable. Quantifying the balance is both desirable and challenging. For example, drift-driven failure, a stochastic force, can be thought of as an organism experiencing ‘bad luck’ and manipul...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251119/ https://www.ncbi.nlm.nih.gov/pubmed/37303747 http://dx.doi.org/10.1098/rsfs.2023.0010 |
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author | Weaver, Joseph Earl |
author_facet | Weaver, Joseph Earl |
author_sort | Weaver, Joseph Earl |
collection | PubMed |
description | Both deterministic and stochastic forces shape biofilm communities, but the balance between those forces is variable. Quantifying the balance is both desirable and challenging. For example, drift-driven failure, a stochastic force, can be thought of as an organism experiencing ‘bad luck’ and manipulating ‘luck’ as a factor in real-world systems is difficult. We used an agent-based model to manipulate luck by controlling seed cevalues governing random number generation. We determined which organism among identical competitors experienced the greatest drift-driven failure, gave it a deterministic growth advantage and re-ran the simulation with the same seed. This enabled quantifying the growth advantage required to overcome drift, e.g. a 50% chance to thrive may require a 10–20% improved growth rate. Further, we found that crowding intensity affected that balance. At moderate spacings, there were wide ranges where neither drift nor selection dominated. Those ranges shrank at extreme spacings; close and loose crowding, respectively, favoured drift and selection. We explain how these results may partially illuminate two conundrums: the fact that a stably operating wastewater treatment plant's microbial community can vary greatly over time and the difference between equivalent and total community size in neutral community assembly models. |
format | Online Article Text |
id | pubmed-10251119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-102511192023-06-10 Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions Weaver, Joseph Earl Interface Focus Articles Both deterministic and stochastic forces shape biofilm communities, but the balance between those forces is variable. Quantifying the balance is both desirable and challenging. For example, drift-driven failure, a stochastic force, can be thought of as an organism experiencing ‘bad luck’ and manipulating ‘luck’ as a factor in real-world systems is difficult. We used an agent-based model to manipulate luck by controlling seed cevalues governing random number generation. We determined which organism among identical competitors experienced the greatest drift-driven failure, gave it a deterministic growth advantage and re-ran the simulation with the same seed. This enabled quantifying the growth advantage required to overcome drift, e.g. a 50% chance to thrive may require a 10–20% improved growth rate. Further, we found that crowding intensity affected that balance. At moderate spacings, there were wide ranges where neither drift nor selection dominated. Those ranges shrank at extreme spacings; close and loose crowding, respectively, favoured drift and selection. We explain how these results may partially illuminate two conundrums: the fact that a stably operating wastewater treatment plant's microbial community can vary greatly over time and the difference between equivalent and total community size in neutral community assembly models. The Royal Society 2023-06-09 /pmc/articles/PMC10251119/ /pubmed/37303747 http://dx.doi.org/10.1098/rsfs.2023.0010 Text en © 2023 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Articles Weaver, Joseph Earl Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title | Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title_full | Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title_fullStr | Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title_full_unstemmed | Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title_short | Quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
title_sort | quantifying drift-selection balance using an agent-based biofilm model of identical heterotrophs under low-nutrient conditions |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251119/ https://www.ncbi.nlm.nih.gov/pubmed/37303747 http://dx.doi.org/10.1098/rsfs.2023.0010 |
work_keys_str_mv | AT weaverjosephearl quantifyingdriftselectionbalanceusinganagentbasedbiofilmmodelofidenticalheterotrophsunderlownutrientconditions |