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Stiffened fibre-like microenvironment based on patterned equidistant micropillars directs chondrocyte hypertrophy
Articular cartilage, composed of collagen type II as a major extracellular matrix and chondrocyte as a unique cell type, is a specialized connective tissue without blood vessels, lymphatic vessels and nerves. This distinctive characteristic of articular cartilage determines its very limited ability...
Autores principales: | Duan, Mengmeng, Xia, Shuang, Liu, Yang, Pu, Xiaohua, Chen, Yukun, Zhou, Yilin, Huang, Minglei, Pi, Caixia, Zhang, Demao, Xie, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251154/ https://www.ncbi.nlm.nih.gov/pubmed/37304578 http://dx.doi.org/10.1016/j.mtbio.2023.100682 |
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