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Alterations in cytoskeletal and Ca(2+) cycling regulators in atria lacking the obscurin Ig58/59 module
INTRODUCTION: Obscurin (720–870 kDa) is a giant cytoskeletal and signaling protein that possesses both structural and regulatory functions in striated muscles. Immunoglobulin domains 58/59 (Ig58/59) of obscurin bind to a diverse set of proteins that are essential for the proper structure and functio...
Autores principales: | Grogan, Alyssa, Huang, Weiliang, Brong, Annie, Kane, Maureen A., Kontrogianni-Konstantopoulos, Aikaterini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251194/ https://www.ncbi.nlm.nih.gov/pubmed/37304957 http://dx.doi.org/10.3389/fcvm.2023.1085840 |
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