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Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of potassium ferrocyanide as a technological feed additive, functional group anticaking agents, for all animal species. The additive potassium ferrocyanide is intended to be us...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Aquilina, Gabriele, Bories, Georges, Nebbia, Carlo, Gropp, Jürgen, Galobart, Jaume, Vettori, Maria Vittoria, Anguita, Montserrat, Ortuño Casanova, Jordi, Amaduzzi, Angelica, Innocenti, Matteo Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251259/
https://www.ncbi.nlm.nih.gov/pubmed/37304350
http://dx.doi.org/10.2903/j.efsa.2023.7953
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Aquilina, Gabriele
Bories, Georges
Nebbia, Carlo
Gropp, Jürgen
Galobart, Jaume
Vettori, Maria Vittoria
Anguita, Montserrat
Ortuño Casanova, Jordi
Amaduzzi, Angelica
Innocenti, Matteo Lorenzo
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Aquilina, Gabriele
Bories, Georges
Nebbia, Carlo
Gropp, Jürgen
Galobart, Jaume
Vettori, Maria Vittoria
Anguita, Montserrat
Ortuño Casanova, Jordi
Amaduzzi, Angelica
Innocenti, Matteo Lorenzo
collection PubMed
description Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of potassium ferrocyanide as a technological feed additive, functional group anticaking agents, for all animal species. The additive potassium ferrocyanide is intended to be used in potassium chloride with a maximum content of 150 mg ferrocyanide anion/kg salt. The use of potassium ferrocyanide is safe, when added to potassium chloride at a maximum content of 150 mg ferrocyanide anions (anhydrous)/kg for: pigs for fattening and lactating sows, sheep, goats, salmon and dogs. In the absence of a margin of safety, the use of potassium chloride according to the proposed conditions of use is not considered to be safe for chickens for fattening, laying hens, turkeys, piglets, veal calf, cattle for fattening, dairy cows, horse, rabbit and cats. In the absence of information on the use of potassium chloride in the diets for any other animal species, no conclusion on a potentially safe level of potassium chloride, supplemented with 150 mg ferrocyanide/kg, can be made. The use of potassium ferrocyanide in animal nutrition is of no concern for consumer safety. The results of in vivo studies showed that potassium ferrocyanide is not irritant to skin and eye and is not a skin sensitiser. However, due to the presence of nickel, the additive should be considered as a respiratory and dermal sensitiser. The available data do not allow the FEEDAP Panel to conclude on the safety of the additive for the soil and the marine environment, while the use of the additive in land‐based aquaculture according to the proposed conditions of use is considered of no concern. Potassium ferrocyanide is considered to be efficacious as an anticaking agent when included in potassium chloride at the proposed use levels.
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spelling pubmed-102512592023-06-10 Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Aquilina, Gabriele Bories, Georges Nebbia, Carlo Gropp, Jürgen Galobart, Jaume Vettori, Maria Vittoria Anguita, Montserrat Ortuño Casanova, Jordi Amaduzzi, Angelica Innocenti, Matteo Lorenzo EFSA J Scientific Opinion Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of potassium ferrocyanide as a technological feed additive, functional group anticaking agents, for all animal species. The additive potassium ferrocyanide is intended to be used in potassium chloride with a maximum content of 150 mg ferrocyanide anion/kg salt. The use of potassium ferrocyanide is safe, when added to potassium chloride at a maximum content of 150 mg ferrocyanide anions (anhydrous)/kg for: pigs for fattening and lactating sows, sheep, goats, salmon and dogs. In the absence of a margin of safety, the use of potassium chloride according to the proposed conditions of use is not considered to be safe for chickens for fattening, laying hens, turkeys, piglets, veal calf, cattle for fattening, dairy cows, horse, rabbit and cats. In the absence of information on the use of potassium chloride in the diets for any other animal species, no conclusion on a potentially safe level of potassium chloride, supplemented with 150 mg ferrocyanide/kg, can be made. The use of potassium ferrocyanide in animal nutrition is of no concern for consumer safety. The results of in vivo studies showed that potassium ferrocyanide is not irritant to skin and eye and is not a skin sensitiser. However, due to the presence of nickel, the additive should be considered as a respiratory and dermal sensitiser. The available data do not allow the FEEDAP Panel to conclude on the safety of the additive for the soil and the marine environment, while the use of the additive in land‐based aquaculture according to the proposed conditions of use is considered of no concern. Potassium ferrocyanide is considered to be efficacious as an anticaking agent when included in potassium chloride at the proposed use levels. John Wiley and Sons Inc. 2023-06-09 /pmc/articles/PMC10251259/ /pubmed/37304350 http://dx.doi.org/10.2903/j.efsa.2023.7953 Text en © 2023 European Food Safety Authority. EFSA Journal published by Wiley‐VCH GmbH on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Aquilina, Gabriele
Bories, Georges
Nebbia, Carlo
Gropp, Jürgen
Galobart, Jaume
Vettori, Maria Vittoria
Anguita, Montserrat
Ortuño Casanova, Jordi
Amaduzzi, Angelica
Innocenti, Matteo Lorenzo
Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title_full Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title_fullStr Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title_full_unstemmed Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title_short Safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (K + S KALI GmbH)
title_sort safety and efficacy of a feed additive consisting of potassium ferrocyanide for all animal species (k + s kali gmbh)
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251259/
https://www.ncbi.nlm.nih.gov/pubmed/37304350
http://dx.doi.org/10.2903/j.efsa.2023.7953
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