Differential effect of lactate on synovial fibroblast and macrophage effector functions

INTRODUCTION: The synovial membrane is the main site of inflammation in rheumatoid arthritis (RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions, have been recently identified. The RA synovium is hypoxic and acidic, with increased levels of lactate as a result...

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Detalles Bibliográficos
Autores principales: Pucino, Valentina, Nefla, Meriam, Gauthier, Vincent, Alsaleh, Ghada, Clayton, Sally A., Marshall, Jennifer, Filer, Andrew, Clark, Andy R., Raza, Karim, Buckley, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251493/
https://www.ncbi.nlm.nih.gov/pubmed/37304267
http://dx.doi.org/10.3389/fimmu.2023.1183825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251493/
https://www.ncbi.nlm.nih.gov/pubmed/37304267
http://dx.doi.org/10.3389/fimmu.2023.1183825

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