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Driving the conversion of phytosterol to 9α-hydroxy-4-androstene-3,17-dione in Mycolicibacterium neoaurum by engineering the supply and regeneration of flavin adenine dinucleotide

BACKGROUND: The conversion of phytosterols to steroid synthons by engineered Mycolicibacteria comprises one of the core steps in the commercial production of steroid hormones. This is a complex oxidative catabolic process, and taking the production of androstenones as example, it requires about 10 e...

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Detalles Bibliográficos
Autores principales:	Song, Lu, Ke, Jie, Luo, Zhi-Kun, Xiong, Liang-Bin, Dong, Yu-Guo, Wei, Dong-Zhi, Wang, Feng-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251532/ https://www.ncbi.nlm.nih.gov/pubmed/37291661 http://dx.doi.org/10.1186/s13068-023-02331-1

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