Genome-wide DNA methylation profiling of CD4(+) T lymphocytes identifies differentially methylated loci associated with adult primary refractory immune thrombocytopenia

BACKGROUND: DNA methylation played a crucial role in the pathogenesis of immune thrombocytopenia (ITP). However, genome-wide DNA methylation analysis has not been applied thus far. The present study aimed to provide the first DNA methylation profiling for ITP. METHODS: Peripheral blood CD4(+) T lymp...

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Detalles Bibliográficos
Autores principales: Du, Hanzhi, Tang, Qinghua, Yang, Jian, Yan, Bin, Yang, Lihong, Wang, Mengchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251572/
https://www.ncbi.nlm.nih.gov/pubmed/37291547
http://dx.doi.org/10.1186/s12920-023-01557-0

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