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A multi-tissue gene expression dataset for hibernating brown bears

OBJECTIVES: Complex physiological adaptations often involve the coordination of molecular responses across multiple tissues. Establishing transcriptomic resources for non-traditional model organisms with phenotypes of interest can provide a foundation for understanding the genomic basis of these phe...

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Autores principales: Perry, Blair W., Saxton, Michael W., Jansen, Heiko T., Quackenbush, Corey R., Evans Hutzenbiler, Brandon D., Robbins, Charles T., Kelley, Joanna L., Cornejo, Omar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251632/
https://www.ncbi.nlm.nih.gov/pubmed/37291509
http://dx.doi.org/10.1186/s12863-023-01136-3
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author Perry, Blair W.
Saxton, Michael W.
Jansen, Heiko T.
Quackenbush, Corey R.
Evans Hutzenbiler, Brandon D.
Robbins, Charles T.
Kelley, Joanna L.
Cornejo, Omar E.
author_facet Perry, Blair W.
Saxton, Michael W.
Jansen, Heiko T.
Quackenbush, Corey R.
Evans Hutzenbiler, Brandon D.
Robbins, Charles T.
Kelley, Joanna L.
Cornejo, Omar E.
author_sort Perry, Blair W.
collection PubMed
description OBJECTIVES: Complex physiological adaptations often involve the coordination of molecular responses across multiple tissues. Establishing transcriptomic resources for non-traditional model organisms with phenotypes of interest can provide a foundation for understanding the genomic basis of these phenotypes, and the degree to which these resemble, or contrast, those of traditional model organisms. Here, we present a one-of-a-kind gene expression dataset generated from multiple tissues of two hibernating brown bears (Ursus arctos). DATA DESCRIPTION: This dataset is comprised of 26 samples collected from 13 tissues of two hibernating brown bears. These samples were collected opportunistically and are typically not possible to attain, resulting in a highly unique and valuable gene expression dataset. In combination with previously published datasets, this new transcriptomic resource will facilitate detailed investigation of hibernation physiology in bears, and the potential to translate aspects of this biology to treat human disease.
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spelling pubmed-102516322023-06-10 A multi-tissue gene expression dataset for hibernating brown bears Perry, Blair W. Saxton, Michael W. Jansen, Heiko T. Quackenbush, Corey R. Evans Hutzenbiler, Brandon D. Robbins, Charles T. Kelley, Joanna L. Cornejo, Omar E. BMC Genom Data Data Note OBJECTIVES: Complex physiological adaptations often involve the coordination of molecular responses across multiple tissues. Establishing transcriptomic resources for non-traditional model organisms with phenotypes of interest can provide a foundation for understanding the genomic basis of these phenotypes, and the degree to which these resemble, or contrast, those of traditional model organisms. Here, we present a one-of-a-kind gene expression dataset generated from multiple tissues of two hibernating brown bears (Ursus arctos). DATA DESCRIPTION: This dataset is comprised of 26 samples collected from 13 tissues of two hibernating brown bears. These samples were collected opportunistically and are typically not possible to attain, resulting in a highly unique and valuable gene expression dataset. In combination with previously published datasets, this new transcriptomic resource will facilitate detailed investigation of hibernation physiology in bears, and the potential to translate aspects of this biology to treat human disease. BioMed Central 2023-06-08 /pmc/articles/PMC10251632/ /pubmed/37291509 http://dx.doi.org/10.1186/s12863-023-01136-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Data Note
Perry, Blair W.
Saxton, Michael W.
Jansen, Heiko T.
Quackenbush, Corey R.
Evans Hutzenbiler, Brandon D.
Robbins, Charles T.
Kelley, Joanna L.
Cornejo, Omar E.
A multi-tissue gene expression dataset for hibernating brown bears
title A multi-tissue gene expression dataset for hibernating brown bears
title_full A multi-tissue gene expression dataset for hibernating brown bears
title_fullStr A multi-tissue gene expression dataset for hibernating brown bears
title_full_unstemmed A multi-tissue gene expression dataset for hibernating brown bears
title_short A multi-tissue gene expression dataset for hibernating brown bears
title_sort multi-tissue gene expression dataset for hibernating brown bears
topic Data Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251632/
https://www.ncbi.nlm.nih.gov/pubmed/37291509
http://dx.doi.org/10.1186/s12863-023-01136-3
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