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Pervasive effects of RNA degradation on Nanopore direct RNA sequencing

Oxford Nanopore direct RNA sequencing (DRS) is capable of sequencing complete RNA molecules and accurately measuring gene and isoform expression. However, as DRS is designed to profile intact RNA, expression quantification may be more heavily dependent upon RNA integrity than alternative RNA sequenc...

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Detalles Bibliográficos
Autores principales:	Prawer, Yair D J, Gleeson, Josie, De Paoli-Iseppi, Ricardo, Clark, Michael B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Standard Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251640/ https://www.ncbi.nlm.nih.gov/pubmed/37305170 http://dx.doi.org/10.1093/nargab/lqad060

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