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Deformable titanium for acetabular revision surgery: a proof of concept

Custom-made triflange acetabular implants are increasingly used in complex revision surgery where supporting bone stock is diminished. In most cases these triflange cups induce stress-shielding. A new concept for the triflange is introduced that uses deformable porous titanium to redirect forces fro...

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Autores principales: Magré, J., Willemsen, K., Kolken, H. M. A., Zadpoor, A. A., Vogely, H. C., van der Wal, B. C. H., Weinans, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251654/
https://www.ncbi.nlm.nih.gov/pubmed/37294496
http://dx.doi.org/10.1186/s41205-023-00177-9
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author Magré, J.
Willemsen, K.
Kolken, H. M. A.
Zadpoor, A. A.
Vogely, H. C.
van der Wal, B. C. H.
Weinans, H.
author_facet Magré, J.
Willemsen, K.
Kolken, H. M. A.
Zadpoor, A. A.
Vogely, H. C.
van der Wal, B. C. H.
Weinans, H.
author_sort Magré, J.
collection PubMed
description Custom-made triflange acetabular implants are increasingly used in complex revision surgery where supporting bone stock is diminished. In most cases these triflange cups induce stress-shielding. A new concept for the triflange is introduced that uses deformable porous titanium to redirect forces from the acetabular rim to the bone stock behind the implant and thereby reduces further stress-shielding. This concept is tested for deformability and primary stability. Three different designs of highly porous titanium cylinders were tested under compression to determine their mechanical properties. The most promising design was used to design five acetabular implants either by incorporating a deformable layer at the back of the implant or by adding a separate generic deformable mesh behind the implant. All implants were inserted into sawbones with acetabular defects followed by a cyclic compression test of 1800N for 1000 cycles. The design with a cell size of 4 mm and 0.2 mm strut thickness performed the best and was applied for the design of the acetabular implants. An immediate primary fixation was realized in all three implants with an incorporated deformable layer. One of the two implants with a separate deformable mesh needed fixation with screws. Cyclic tests revealed an average additional implant subsidence of 0.25 mm that occurred in the first 1000 cycles with minimal further subsidence thereafter. It is possible to realize primary implant fixation and stability in simulated large acetabular revision surgery using a deformable titanium layer behind the cup. Additional research is needed for further implementation of such implants in the clinic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41205-023-00177-9.
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spelling pubmed-102516542023-06-10 Deformable titanium for acetabular revision surgery: a proof of concept Magré, J. Willemsen, K. Kolken, H. M. A. Zadpoor, A. A. Vogely, H. C. van der Wal, B. C. H. Weinans, H. 3D Print Med Research Custom-made triflange acetabular implants are increasingly used in complex revision surgery where supporting bone stock is diminished. In most cases these triflange cups induce stress-shielding. A new concept for the triflange is introduced that uses deformable porous titanium to redirect forces from the acetabular rim to the bone stock behind the implant and thereby reduces further stress-shielding. This concept is tested for deformability and primary stability. Three different designs of highly porous titanium cylinders were tested under compression to determine their mechanical properties. The most promising design was used to design five acetabular implants either by incorporating a deformable layer at the back of the implant or by adding a separate generic deformable mesh behind the implant. All implants were inserted into sawbones with acetabular defects followed by a cyclic compression test of 1800N for 1000 cycles. The design with a cell size of 4 mm and 0.2 mm strut thickness performed the best and was applied for the design of the acetabular implants. An immediate primary fixation was realized in all three implants with an incorporated deformable layer. One of the two implants with a separate deformable mesh needed fixation with screws. Cyclic tests revealed an average additional implant subsidence of 0.25 mm that occurred in the first 1000 cycles with minimal further subsidence thereafter. It is possible to realize primary implant fixation and stability in simulated large acetabular revision surgery using a deformable titanium layer behind the cup. Additional research is needed for further implementation of such implants in the clinic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41205-023-00177-9. Springer International Publishing 2023-06-09 /pmc/articles/PMC10251654/ /pubmed/37294496 http://dx.doi.org/10.1186/s41205-023-00177-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Magré, J.
Willemsen, K.
Kolken, H. M. A.
Zadpoor, A. A.
Vogely, H. C.
van der Wal, B. C. H.
Weinans, H.
Deformable titanium for acetabular revision surgery: a proof of concept
title Deformable titanium for acetabular revision surgery: a proof of concept
title_full Deformable titanium for acetabular revision surgery: a proof of concept
title_fullStr Deformable titanium for acetabular revision surgery: a proof of concept
title_full_unstemmed Deformable titanium for acetabular revision surgery: a proof of concept
title_short Deformable titanium for acetabular revision surgery: a proof of concept
title_sort deformable titanium for acetabular revision surgery: a proof of concept
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251654/
https://www.ncbi.nlm.nih.gov/pubmed/37294496
http://dx.doi.org/10.1186/s41205-023-00177-9
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