Cargando…

CSTF2T facilitates pancreatic adenocarcinoma growth and metastasis by elevating H3K4Me1 methylation of CALB2 via ASH2L

Pancreatic adenocarcinoma (PAAD) is a major cause of mortality related to cancer worldwide. This paper dissected the functions of the CSTF2T/ASH2L/CALB2 axis in PAAD progression. CALB2 expression was assessed in PAAD tissues and cells using RT-qPCR and western blot. Subsequent to gain- and loss-of-f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wei, Hu, Dongwei, Li, Jinjie, Xu, Qigang, Chen, Zongjing, Xu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251778/ https://www.ncbi.nlm.nih.gov/pubmed/37287122 http://dx.doi.org/10.1080/15384047.2023.2216041

Ejemplares similares

The structure of the CstF-77 homodimer provides insights into CstF assembly
por: Legrand, Pierre, et al.
Publicado: (2007)

Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function
por: Ruepp, Marc-David, et al.
Publicado: (2011)

CSTF2 Promotes Hepatocarcinogenesis and Hepatocellular Carcinoma Progression via Aerobic Glycolysis
por: Chen, Zhimin, et al.
Publicado: (2022)

CaLB Catalyzed Conversion of ε-Caprolactone in Aqueous Medium. Part 1: Immobilization of CaLB to Microgels
por: Engel, Stefan, et al.
Publicado: (2016)

The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity
por: Grozdanov, Petar N, et al.
Publicado: (2018)

In silico screening of 393 mutants facilitates enzyme engineering of amidase activity in CalB
por: Hediger, Martin R., et al.
Publicado: (2013)

Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3′ processing
por: Yao, Chengguo, et al.
Publicado: (2013)

A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma
por: Huang, Yangjin, et al.
Publicado: (2023)

Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3′-end processing signals
por: Yang, Wen, et al.
Publicado: (2018)

Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter
por: Blum, Walter, et al.
Publicado: (2018)

Characterization and Localization of Calb2 in Both the Testis and Ovary of the Japanese Flounder (Paralichthys olivaceus)
por: Xiang, Yuting, et al.
Publicado: (2020)

Electrostatic Interactions between CSTF2 and pre-mRNA Drive Cleavage and Polyadenylation
por: Masoumzadeh, Elahe, et al.
Publicado: (2022)

CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma
por: Zhang, Wang, et al.
Publicado: (2022)

CSTF2 mediated mRNA N(6)-methyladenosine modification drives pancreatic ductal adenocarcinoma m(6)A subtypes
por: Zheng, Yanfen, et al.
Publicado: (2023)

Geometric Simulation Approach for Grading and Assessing the Thermostability of CALBs
por: Senthilkumar, B., et al.
Publicado: (2016)

Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway
por: Stevenson, Leanne, et al.
Publicado: (2011)

The Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice
por: Harris, Jaryse C., et al.
Publicado: (2016)

Is Promiscuous CALB a Good Scaffold for Designing New Epoxidases?
por: Bordes, Isabel, et al.
Publicado: (2015)

Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway
por: Yang, Mengdi, et al.
Publicado: (2020)

CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells
por: Cao, Long-Qiao, et al.
Publicado: (2019)

Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca(2+) Levels in Senescent Cells
por: Raynard, Clotilde, et al.
Publicado: (2022)

The 3′ processing factor CstF functions in the DNA repair response
por: Mirkin, Nurit, et al.
Publicado: (2008)

KIF2C Facilitates Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma
por: Huang, Xing, et al.
Publicado: (2023)

The τCstF-64 Polyadenylation Protein Controls Genome Expression in Testis
por: Li, Wencheng, et al.
Publicado: (2012)

A Novel CalB-Type Lipase Discovered by Fungal Genomes Mining
por: Vaquero, Maria E., et al.
Publicado: (2015)

Combined Effects of Ultrasound and Immobilization Protocol on Butyl Acetate Synthesis Catalyzed by CALB
por: Alves, Joana S., et al.
Publicado: (2014)

Dissecting the evolvability landscape of the CalB active site toward aromatic substrates
por: Santos, Yossef López de los, et al.
Publicado: (2019)

A family of splice variants of CstF-64 expressed in vertebrate nervous systems
por: Shankarling, Ganesh S, et al.
Publicado: (2009)

Fast Degradation of Bisphenol A in Water by Nanostructured CuNPs@CALB Biohybrid Catalysts
por: Losada-Garcia, Noelia, et al.
Publicado: (2019)

Energetic and Kinetic Origins of CALB Interfacial Activation Revealed by PaCS-MD/MSM
por: Wijaya, Tegar N., et al.
Publicado: (2023)

The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50
por: Edwards, Ross A., et al.
Publicado: (2008)

The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50
por: Edwards, R. A., et al.
Publicado: (2009)

Stabilization of Candida antarctica Lipase B (CALB) Immobilized on Octyl Agarose by Treatment with Polyethyleneimine (PEI)
por: Peirce, Sara, et al.
Publicado: (2016)

Immobilization of CALB on activated chitosan: Application to enzymatic synthesis in supercritical and near-critical carbon dioxide
por: dos Santos, José C.S., et al.
Publicado: (2017)

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50
por: Choudhary, Rajan Kumar, et al.
Publicado: (2017)

Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients
por: Castrogiovanni, Paola, et al.
Publicado: (2021)

Coadaptation fostered by the SLIT2-ROBO1 axis facilitates liver metastasis of pancreatic ductal adenocarcinoma
por: Li, Qing, et al.
Publicado: (2023)

Performance of Fly Ash Geopolymer Concrete Incorporating Bamboo Ash at Elevated Temperature
por: Ishak, Shafiq, et al.
Publicado: (2019)

sCLIP—an integrated platform to study RNA–protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs
por: Kargapolova, Yulia, et al.
Publicado: (2017)

Strep-tag II fusion technology for the modification and immobilization of lipase B from Candida antarctica (CALB)
por: Johar, Sumreet Singh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7l9p7vtaa98qdhvh1180irk7t9