Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies

Specific HBsAg mutations are known to hamper HBsAg recognition by neutralizing antibodies thus challenging HBV-vaccination efficacy. Nevertheless, information on their impact and spreading over time is limited. Here, we characterize the circulation of vaccine-escape mutations from 2005 to 2019 and t...

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Detalles Bibliográficos
Autores principales: Piermatteo, Lorenzo, D’Anna, Stefano, Bertoli, Ada, Bellocchi, Maria, Carioti, Luca, Fabeni, Lavinia, Alkhatib, Mohammad, Frazia, Simone La, Lichtner, Miriam, Mastroianni, Claudio, Sanctis, Giuseppe De, Marignani, Massimo, Pasquazzi, Caterina, Iapadre, Nerio, Parruti, Giustino, Cappiello, Giuseppina, Vecchiet, Jacopo, Malagnino, Vincenzo, Grelli, Sandro, Ceccherini-Silbertein, Francesca, Andreoni, Massimo, Sarmati, Loredana, Svicher, Valentina, Salpini, Romina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Hepatitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251786/
https://www.ncbi.nlm.nih.gov/pubmed/37288750
http://dx.doi.org/10.1080/22221751.2023.2219347

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