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TERT Expression Induces Resistance to BRAF and MEK Inhibitors in BRAF-Mutated Melanoma In Vitro

SIMPLE SUMMARY: TERT promoter mutations are the most frequent mutations in melanoma, co-occur regularly with BRAF alterations and are associated with a poorer prognosis. Conflicting results have been published on the role of TERT promoter mutations in resistance to targeted therapy in melanoma. Our...

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Detalles Bibliográficos
Autores principales:	Delyon, Julie, Vallet, Anaïs, Bernard-Cacciarella, Mélanie, Kuzniak, Isabelle, Reger de Moura, Coralie, Louveau, Baptiste, Jouenne, Fanélie, Mourah, Samia, Lebbé, Céleste, Dumaz, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251862/ https://www.ncbi.nlm.nih.gov/pubmed/37296851 http://dx.doi.org/10.3390/cancers15112888

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