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Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stromal Cells as an Efficient Nanocarrier to Deliver siRNA or Drug to Pancreatic Cancer Cells

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. Treatment of PDAC remains a major challenge. Recently, exosomes derived from mouse skin fibroblasts were modified to deliver siRNA to specifically target mutant KRAS. This approach resulted in diseas...

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Detalles Bibliográficos
Autores principales:	Draguet, Florian, Dubois, Nathan, Bouland, Cyril, Pieters, Karlien, Bron, Dominique, Meuleman, Nathalie, Stamatopoulos, Basile, Lagneaux, Laurence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251888/ https://www.ncbi.nlm.nih.gov/pubmed/37296864 http://dx.doi.org/10.3390/cancers15112901

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