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Mutation in the Common Docking Domain Affects MAP Kinase ERK2 Catalysis and Stability

SIMPLE SUMMARY: The extracellular-signal-regulated kinase 2 (ERK2) plays a key role in the Ras-Raf-MEK-ERK signal transduction cascade and is involved in the regulation of many cellular processes. The ERK2 signaling converts extracellular stimuli into cell proliferation and, when deregulated, can pr...

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Detalles Bibliográficos
Autores principales:	Novak, Leonore, Petrosino, Maria, Pasquo, Alessandra, Chaikuad, Apirat, Chiaraluce, Roberta, Knapp, Stefan, Consalvi, Valerio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252016/ https://www.ncbi.nlm.nih.gov/pubmed/37296900 http://dx.doi.org/10.3390/cancers15112938

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