Mutant IDH in Gliomas: Role in Cancer and Treatment Options

SIMPLE SUMMARY: Isocitrate dehydrogenase (IDH) is the most mutated metabolic gene in human cancer. Mutations in this gene have been identified in a high percentage of gliomas, in acute myeloid leukemia (AML) and in many other malignancies. Mutant IDH causes tumour initiation, possibly through accumu...

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Detalles Bibliográficos
Autores principales: Solomou, Georgios, Finch, Alina, Asghar, Asim, Bardella, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252079/
https://www.ncbi.nlm.nih.gov/pubmed/37296846
http://dx.doi.org/10.3390/cancers15112883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252079/
https://www.ncbi.nlm.nih.gov/pubmed/37296846
http://dx.doi.org/10.3390/cancers15112883

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