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Mutant IDH in Gliomas: Role in Cancer and Treatment Options
SIMPLE SUMMARY: Isocitrate dehydrogenase (IDH) is the most mutated metabolic gene in human cancer. Mutations in this gene have been identified in a high percentage of gliomas, in acute myeloid leukemia (AML) and in many other malignancies. Mutant IDH causes tumour initiation, possibly through accumu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252079/ https://www.ncbi.nlm.nih.gov/pubmed/37296846 http://dx.doi.org/10.3390/cancers15112883 |