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Folic Acid Supplementation Promotes Hypomethylation in Both the Inflamed Colonic Mucosa and Colitis-Associated Dysplasia

SIMPLE SUMMARY: Ulcerative colitis, a form of inflammatory bowel disease, is a major risk factor for developing colorectal cancer. Patients with ulcerative colitis often present with low serum folate levels due to the adverse effect of maintenance therapies and/or intestinal malabsorption and requir...

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Detalles Bibliográficos
Autores principales: Chang, Wen-Chi L., Ghosh, Jayashri, Cooper, Harry S., Vanderveer, Lisa, Schultz, Bryant, Zhou, Yan, Harvey, Kristen N., Kaunga, Esther, Devarajan, Karthik, Li, Yuesheng, Jelinek, Jaroslav, Fragoso, Mariana F., Sapienza, Carmen, Clapper, Margie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252136/
https://www.ncbi.nlm.nih.gov/pubmed/37296911
http://dx.doi.org/10.3390/cancers15112949