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Generation of an Obese Diabetic Mouse Model upon Conditional Atrx Disruption

SIMPLE SUMMARY: ATRX mutations occur in up to 17% of human pancreatic neuroendocrine tumours (PanNETs), and recent evidence points towards its inability to drive PanNET formation in mouse pancreas while predisposing individuals to inflammageing. Aiming to explore the additional non-tumourigenic cons...

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Detalles Bibliográficos
Autores principales:	Gaspar, Tiago Bordeira, Jesus, Tito Teles, Azevedo, Maria Teresa, Macedo, Sofia, Soares, Mariana Alves, Martins, Rui Sousa, Leite, Rúben, Rodrigues, Lia, Rodrigues, Daniela Ferreira, Cardoso, Luís, Borges, Inês, Canberk, Sule, Gärtner, Fátima, Miranda-Alves, Leandro, Lopes, José Manuel, Soares, Paula, Vinagre, João
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252256/ https://www.ncbi.nlm.nih.gov/pubmed/37296979 http://dx.doi.org/10.3390/cancers15113018

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