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Homologous Recombination Deficiency Score Determined by Genomic Instability in a Romanian Cohort
The Homologous Recombination Deficiency (HRD) Score, determined by evaluating genomic instability through the assessment of loss of heterozygosity (LOH), telomeric allelic imbalance (TAI), and large-scale state transitions (LST), serves as a crucial biomarker for identifying patients who might benef...
Autores principales: | Rădoi, Viorica-Elena, Țurcan, Mihaela, Maioru, Ovidiu Virgil, Dan, Andra, Bohîlțea, Laurentiu Camil, Dumitrescu, Elena Adriana, Gheorghe, Adelina Silvana, Stănculeanu, Dana Lucia, Thodi, Georgia, Loukas, Yannis L., Săbău, Ileana-Delia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252278/ https://www.ncbi.nlm.nih.gov/pubmed/37296748 http://dx.doi.org/10.3390/diagnostics13111896 |
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