Cargando…

IRF3 Activation in Mast Cells Promotes FcεRI-Mediated Allergic Inflammation

(1) Background: This study aims to elucidate a novel non-transcriptional action of IRF3 in addition to its role as a transcription factor in mast cell activation and associated allergic inflammation; (2) Methods: For in vitro experiments, mouse bone-marrow-derived mast cells (mBMMCs) and a rat basop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Young-Ae, Dhakal, Hima, Lee, Soyoung, Kim, Namkyung, Lee, Byungheon, Kwon, Taeg Kyu, Khang, Dongwoo, Kim, Sang-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252328/ https://www.ncbi.nlm.nih.gov/pubmed/37296614 http://dx.doi.org/10.3390/cells12111493

Ejemplares similares

Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels
por: Dhakal, Hima, et al.
Publicado: (2019)

Avenanthramide C from germinated oats exhibits anti-allergic inflammatory effects in mast cells
por: Dhakal, Hima, et al.
Publicado: (2019)

Elaeocarpusin Inhibits Mast Cell-Mediated Allergic Inflammation
por: Kim, Min-Jong, et al.
Publicado: (2018)

SG-SP1 Suppresses Mast Cell-Mediated Allergic Inflammation via Inhibition of FcεRI Signaling
por: Kim, Min-Jong, et al.
Publicado: (2020)

New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling
por: Li, Yang, et al.
Publicado: (2022)

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes
por: Lecce, Mario, et al.
Publicado: (2020)

Gomisin M2 alleviates psoriasis-like skin inflammation by inhibiting inflammatory signaling pathways
por: Kim, Namkyung, et al.
Publicado: (2021)

FcεRI: A Master Regulator of Mast Cell Functions
por: Nagata, Yuka, et al.
Publicado: (2022)

Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell–mediated allergic response
por: Wang, Di, et al.
Publicado: (2014)

Observing Fcεri Signaling from the Inside of the Mast Cell Membrane
por: Wilson, Bridget S., et al.
Publicado: (2000)

Fine-Tuning of Mast Cell Activation by FcεRIβ Chain
por: Ra, Chisei, et al.
Publicado: (2012)

The Role Played by Mitochondria in FcεRI-Dependent Mast Cell Activation
por: Chelombitko, Maria A., et al.
Publicado: (2020)

Ethanol Inhibits High-Affinity Immunoglobulin E Receptor (FcεRI) Signaling in Mast Cells by Suppressing the Function of FcεRI-Cholesterol Signalosome
por: Draberova, Lubica, et al.
Publicado: (2015)

The Crosstalk between FcεRI and Sphingosine Signaling in Allergic Inflammation
por: Jo, Hyein, et al.
Publicado: (2022)

Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction
por: Qian, Fei, et al.
Publicado: (2019)

Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic Inflammation
por: Wang, Hui-Na, et al.
Publicado: (2022)

Differential mast cell outcomes are sensitive to FcεRI-Syk binding kinetics
por: Schwartz, Samantha L., et al.
Publicado: (2017)

Corrigendum: The Role Played by Mitochondria in FcϵRI-Dependent Mast Cell Activation
por: Chelombitko, Maria A., et al.
Publicado: (2020)

Eucalyptus oil reduces allergic reactions and suppresses mast cell degranulation by downregulating IgE-FcεRI signalling
por: Nakamura, Tomoya, et al.
Publicado: (2020)

Regulation of Trafficking and Signaling of the High Affinity IgE Receptor by FcεRIβ and the Potential Impact of FcεRIβ Splicing in Allergic Inflammation
por: Arthur, Greer K., et al.
Publicado: (2022)

Rcan1 negatively regulates FcεRI-mediated signaling and mast cell function
por: Yang, Yong Jun, et al.
Publicado: (2009)

Cigarette Smoke Suppresses the Surface Expression of c-kit and FcεRI on Mast Cells
por: Givi, M. E., et al.
Publicado: (2013)

Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation
por: Phong, Binh L., et al.
Publicado: (2015)

Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcεRI and SHIP1
por: Nagata, Kazuki, et al.
Publicado: (2023)

Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation
por: Hong, Jung Yeon, et al.
Publicado: (2016)

Gomisin M2 Ameliorates Atopic Dermatitis-like Skin Lesions via Inhibition of STAT1 and NF-κB Activation in 2,4-Dinitrochlorobenzene/Dermatophagoides farinae Extract-Induced BALB/c Mice
por: Kang, Jinjoo, et al.
Publicado: (2021)

Rehmannia Glutinosa Pharmacopuncture Solution Regulates Functional Activation, FcεRI Expression, and Signaling Events in Mast Cells
por: Kang, Kyung-Hwa, et al.
Publicado: (2012)

Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production
por: Hata, Daisuke, et al.
Publicado: (1998)

GRK2 differentially regulates FcεRI and MRGPRB2-mediated responses in mast cells
por: Thapaliya, Monica, et al.
Publicado: (2023)

Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes
por: Li, Xian, et al.
Publicado: (2017)

SLAP Is a Negative Regulator of FcεRI Receptor-Mediated Signaling and Allergic Response
por: Sharma, Namit, et al.
Publicado: (2019)

An Interaction Library for the FcεRI Signaling Network
por: Chylek, Lily A., et al.
Publicado: (2014)

Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11
por: Sayama, Koichi, et al.
Publicado: (2002)

Overexpression of FcεRI on Bone Marrow Mast Cells, but Not MRGPRX2, in Clonal Mast Cell Disorders With Wasp Venom Anaphylaxis
por: Elst, Jessy, et al.
Publicado: (2022)

High resolution mapping of mast cell membranes reveals primary and secondary domains of FcεRI and LAT
por: Wilson, Bridget S., et al.
Publicado: (2001)

Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells
por: Solís-López, A., et al.
Publicado: (2017)

Antigen Geometry Tunes Mast Cell Signaling Through Distinct FcεRI Aggregation and Structural Changes
por: Rinaldi, Derek A., et al.
Publicado: (2023)

Current Strategies to Inhibit High Affinity FcεRI-Mediated Signaling for the Treatment of Allergic Disease
por: Gomez, Gregorio
Publicado: (2019)

Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes
por: Li, Xian, et al.
Publicado: (2020)

Tyrosol Suppresses Allergic Inflammation by Inhibiting the Activation of Phosphoinositide 3-Kinase in Mast Cells
por: Je, In-Gyu, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n8tutmgegcb944qh9mnkostcsl