Cargando…

Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies

Lymphoid malignancies are a group of highly heterogeneous diseases frequently associated with constitutive activation of the nuclear factor kappa B (NF-κB) signaling pathway. Parthenolide is a natural compound used to treat migraines and arthritis and found to act as a potent NF-κB signaling inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jorge, Joana, Neves, Joana, Alves, Raquel, Geraldes, Catarina, Gonçalves, Ana Cristina, Sarmento-Ribeiro, Ana Bela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252365/ https://www.ncbi.nlm.nih.gov/pubmed/37298119 http://dx.doi.org/10.3390/ijms24119167

Ejemplares similares

PB1719: NIRAPARIB IN B-CELL LYMPHOID MALIGNANCIES: EXPLORING SYNTHETIC LETHALITY AS TARGET FOR THERAPY
por: Lapa, Beatriz, et al.
Publicado: (2023)

P841: MOLECULAR MECHANISMS OF RESISTANCE TO IMMUNOMODULATORS IN MULTIPLE MYELOMA: AN IN VITRO STUDY
por: Alves, Raquel, et al.
Publicado: (2023)

Combination of Elacridar with Imatinib Modulates Resistance Associated with Drug Efflux Transporters in Chronic Myeloid Leukemia
por: Alves, Raquel, et al.
Publicado: (2022)

Antitumor Effect of Brusatol in Acute Lymphoblastic Leukemia Models Is Triggered by Reactive Oxygen Species Accumulation
por: Jorge, Joana, et al.
Publicado: (2022)

PB1822: INHIBITION OF THE DNA DAMAGE RESPONSE: A POSSIBLE NEW ROUTE IN ACUTE MYELOBLASTIC LEUKEMIA TREATMENT
por: Lapa, Beatriz, et al.
Publicado: (2023)

Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid Leukemia Cell Lines
por: Alves, Raquel, et al.
Publicado: (2023)

P659: BUPARLISIB A PROMISING THERAPEUTIC APPROACH IN CHRONIC MYELOID LEUKEMIA RESISTANT TO IMATINIB
por: Alves, Raquel, et al.
Publicado: (2023)

Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
por: Ribeiro, Hugo, et al.
Publicado: (2023)

Monocytes in the Characterization of Pain in Palliative Patients with Severe Dementia—A Pilot Study
por: Ribeiro, Hugo, et al.
Publicado: (2023)

Zinc Prevents DNA Damage in Normal Cells but Shows Genotoxic and Cytotoxic Effects in Acute Myeloid Leukemia Cells
por: Costa, Maria Inês, et al.
Publicado: (2022)

PB1908: NRF2 INHIBITION IN COMBINATION WITH IBRUTINIB IN THE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA– AN IN VITRO STUDY
por: Jorge, Joana, et al.
Publicado: (2023)

PB1910: TELAGLENASTAT (CB-839) IN MONOTHERAPY AND IN COMBINATION WITH EPIGENETIC MODULATORS OR IBRUTINIB INDUCES CELL DEATH IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS
por: Jorge, Joana, et al.
Publicado: (2023)

AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia Cells
por: Lapa, Beatriz Santos, et al.
Publicado: (2023)

Parthenolide suppresses pancreatic cell growth by autophagy-mediated apoptosis
por: Liu, Weifeng, et al.
Publicado: (2017)

Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring
por: Martins, Ivana, et al.
Publicado: (2021)

MicroRNA signature refine response prediction in CML
por: Alves, Raquel, et al.
Publicado: (2019)

Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients
por: Gonçalves, Ana Cristina, et al.
Publicado: (2021)

The role of CD26 and CD40 expression in therapeutic response - experimental study in oral cancer lines
por: Batista, Joana PN, et al.
Publicado: (2010)

Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis
por: Alves, Raquel, et al.
Publicado: (2022)

Nano Parthenolide Improves Intestinal Barrier Function of Sepsis by Inhibiting Apoptosis and ROS via 5-HTR2A
por: Guo, Ning-Ke, et al.
Publicado: (2023)

Metalloproteinase inhibitors as a potential therapeutic approach in multiple myeloma: a preliminary study
por: Pais, A Sofia, et al.
Publicado: (2010)

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies
por: Sztiller-Sikorska, Malgorzata, et al.
Publicado: (2020)

Parthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro
por: Liu, Jun-Wei, et al.
Publicado: (2010)

Parthenolide leads to proteomic differences in thyroid cancer cells and promotes apoptosis
por: Cui, Meng, et al.
Publicado: (2022)

Apoptosis and (in) Pain—Potential Clinical Implications
por: Ribeiro, Hugo, et al.
Publicado: (2022)

Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson’s Disease Model
por: Arslan, Mehmet Enes, et al.
Publicado: (2023)

Zinc: From Biological Functions to Therapeutic Potential
por: Costa, Maria Inês, et al.
Publicado: (2023)

Oophoropexy to the Round Ligament after Recurrent Adnexal Torsion
por: Gonçalves, Inês Sarmento, et al.
Publicado: (2018)

Innate Lymphoid Cells in the Malignant Melanoma Microenvironment
por: Apraiz, Aintzane, et al.
Publicado: (2020)

Evaluation of the role of mir-34b in modulation of radioresistance in non-small cell lung cancer
por: Silva, Joana B, et al.
Publicado: (2010)

Parthenolide induces apoptosis and lytic cytotoxicity in Epstein-Barr virus-positive Burkitt lymphoma
por: LI, YUAN, et al.
Publicado: (2012)

Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells
por: Yi, Juan, et al.
Publicado: (2022)

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance
por: Alves, Raquel, et al.
Publicado: (2021)

Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines
por: Wyrębska, Anna, et al.
Publicado: (2012)

The Emerging Potential of Parthenolide Nanoformulations in Tumor Therapy
por: An, Tao, et al.
Publicado: (2022)

Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model
por: Kim, In Hee, et al.
Publicado: (2012)

Parthenolide Induces Apoptosis and Cell Cycle Arrest of Human 5637 Bladder Cancer Cells In Vitro
por: Cheng, Guang, et al.
Publicado: (2011)

MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies
por: Sionov, Ronit Vogt
Publicado: (2013)

Commentary: Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
por: Jowett, Geraldine M., et al.
Publicado: (2018)

(E)-13-(4-Aminophenyl)parthenolide
por: Penthala, Narsimha Reddy, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5fa52jiqcadvijj1kej7a6g4vl