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Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study

Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (...

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Autores principales: de Nucci, Germana, Gabbani, Tommaso, Impellizzeri, Giovanna, Deiana, Simona, Biancheri, Paolo, Ottaviani, Laura, Frazzoni, Leonardo, Mandelli, Enzo Domenico, Soriani, Paola, Vecchi, Maurizio, Manes, Gianpiero, Manno, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252418/
https://www.ncbi.nlm.nih.gov/pubmed/37296694
http://dx.doi.org/10.3390/diagnostics13111842
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author de Nucci, Germana
Gabbani, Tommaso
Impellizzeri, Giovanna
Deiana, Simona
Biancheri, Paolo
Ottaviani, Laura
Frazzoni, Leonardo
Mandelli, Enzo Domenico
Soriani, Paola
Vecchi, Maurizio
Manes, Gianpiero
Manno, Mauro
author_facet de Nucci, Germana
Gabbani, Tommaso
Impellizzeri, Giovanna
Deiana, Simona
Biancheri, Paolo
Ottaviani, Laura
Frazzoni, Leonardo
Mandelli, Enzo Domenico
Soriani, Paola
Vecchi, Maurizio
Manes, Gianpiero
Manno, Mauro
author_sort de Nucci, Germana
collection PubMed
description Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC.
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spelling pubmed-102524182023-06-10 Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study de Nucci, Germana Gabbani, Tommaso Impellizzeri, Giovanna Deiana, Simona Biancheri, Paolo Ottaviani, Laura Frazzoni, Leonardo Mandelli, Enzo Domenico Soriani, Paola Vecchi, Maurizio Manes, Gianpiero Manno, Mauro Diagnostics (Basel) Article Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC. MDPI 2023-05-25 /pmc/articles/PMC10252418/ /pubmed/37296694 http://dx.doi.org/10.3390/diagnostics13111842 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Nucci, Germana
Gabbani, Tommaso
Impellizzeri, Giovanna
Deiana, Simona
Biancheri, Paolo
Ottaviani, Laura
Frazzoni, Leonardo
Mandelli, Enzo Domenico
Soriani, Paola
Vecchi, Maurizio
Manes, Gianpiero
Manno, Mauro
Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title_full Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title_fullStr Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title_full_unstemmed Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title_short Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
title_sort linear eus accuracy in preoperative staging of gastric cancer: a retrospective multicenter study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252418/
https://www.ncbi.nlm.nih.gov/pubmed/37296694
http://dx.doi.org/10.3390/diagnostics13111842
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