Strategies for Reducing Toxicity and Enhancing Efficacy of Chimeric Antigen Receptor T Cell Therapy in Hematological Malignancies

Chimeric antigen receptor T cell (CAR-T) therapy in hematologic malignancies has made great progress, but there are still some problems. First, T cells from tumor patients show an exhaustion phenotype; thus, the persistence and function of the CAR-Ts are poor, and achieving a satisfactory curative e...

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Detalles Bibliográficos
Autores principales: Wang, Haobing, Tang, Ling, Kong, Yingjie, Liu, Wen, Zhu, Xiaojian, You, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252534/
https://www.ncbi.nlm.nih.gov/pubmed/37298069
http://dx.doi.org/10.3390/ijms24119115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252534/
https://www.ncbi.nlm.nih.gov/pubmed/37298069
http://dx.doi.org/10.3390/ijms24119115

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