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A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination

Cardiotocography (CTG), which measures the fetal heart rate (FHR) and maternal uterine contractions (UC) simultaneously, is used for monitoring fetal well-being during delivery or antenatally at the third trimester. Baseline FHR and its response to uterine contractions can be used to diagnose fetal...

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Autores principales: Akmal, Haad, Hardalaç, Fırat, Ayturan, Kubilay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252854/
https://www.ncbi.nlm.nih.gov/pubmed/37296783
http://dx.doi.org/10.3390/diagnostics13111931
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author Akmal, Haad
Hardalaç, Fırat
Ayturan, Kubilay
author_facet Akmal, Haad
Hardalaç, Fırat
Ayturan, Kubilay
author_sort Akmal, Haad
collection PubMed
description Cardiotocography (CTG), which measures the fetal heart rate (FHR) and maternal uterine contractions (UC) simultaneously, is used for monitoring fetal well-being during delivery or antenatally at the third trimester. Baseline FHR and its response to uterine contractions can be used to diagnose fetal distress, which may necessitate therapeutic intervention. In this study, a machine learning model based on feature extraction (autoencoder), feature selection (recursive feature elimination), and Bayesian optimization, was proposed to diagnose and classify the different conditions of fetuses (Normal, Suspect, Pathologic) along with the CTG morphological patterns. The model was evaluated on a publicly available CTG dataset. This research also addressed the imbalance nature of the CTG dataset. The proposed model has a potential application as a decision support tool to manage pregnancies. The proposed model resulted in good performance analysis metrics. Using this model with Random Forest resulted in a model accuracy of 96.62% for fetal status classification and 94.96% for CTG morphological pattern classification. In rational terms, the model was able to accurately predict 98% Suspect cases and 98.6% Pathologic cases in the dataset. The combination of predicting and classifying fetal status as well as the CTG morphological patterns shows potential in monitoring high-risk pregnancies.
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spelling pubmed-102528542023-06-10 A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination Akmal, Haad Hardalaç, Fırat Ayturan, Kubilay Diagnostics (Basel) Article Cardiotocography (CTG), which measures the fetal heart rate (FHR) and maternal uterine contractions (UC) simultaneously, is used for monitoring fetal well-being during delivery or antenatally at the third trimester. Baseline FHR and its response to uterine contractions can be used to diagnose fetal distress, which may necessitate therapeutic intervention. In this study, a machine learning model based on feature extraction (autoencoder), feature selection (recursive feature elimination), and Bayesian optimization, was proposed to diagnose and classify the different conditions of fetuses (Normal, Suspect, Pathologic) along with the CTG morphological patterns. The model was evaluated on a publicly available CTG dataset. This research also addressed the imbalance nature of the CTG dataset. The proposed model has a potential application as a decision support tool to manage pregnancies. The proposed model resulted in good performance analysis metrics. Using this model with Random Forest resulted in a model accuracy of 96.62% for fetal status classification and 94.96% for CTG morphological pattern classification. In rational terms, the model was able to accurately predict 98% Suspect cases and 98.6% Pathologic cases in the dataset. The combination of predicting and classifying fetal status as well as the CTG morphological patterns shows potential in monitoring high-risk pregnancies. MDPI 2023-06-01 /pmc/articles/PMC10252854/ /pubmed/37296783 http://dx.doi.org/10.3390/diagnostics13111931 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Akmal, Haad
Hardalaç, Fırat
Ayturan, Kubilay
A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title_full A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title_fullStr A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title_full_unstemmed A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title_short A Fetal Well-Being Diagnostic Method Based on Cardiotocographic Morphological Pattern Utilizing Autoencoder and Recursive Feature Elimination
title_sort fetal well-being diagnostic method based on cardiotocographic morphological pattern utilizing autoencoder and recursive feature elimination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252854/
https://www.ncbi.nlm.nih.gov/pubmed/37296783
http://dx.doi.org/10.3390/diagnostics13111931
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