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Analyses of Genes Critical to Tumor Survival Reveal Potential ‘Supertargets’: Focus on Transcription

SIMPLE SUMMARY: A variety of anticancer therapeutic targets have been identified over the decades. Nevertheless, the complexity of biological regulation dictates the necessity of knowledge about mechanisms specific to a particular tumor type. Using the DepMap CRISPR/Cas9 knockout database, we perfor...

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Detalles Bibliográficos
Autores principales: Chetverina, Darya, Vorobyeva, Nadezhda E., Gyorffy, Balazs, Shtil, Alexander A., Erokhin, Maksim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252933/
https://www.ncbi.nlm.nih.gov/pubmed/37297004
http://dx.doi.org/10.3390/cancers15113042

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