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Analyses of Genes Critical to Tumor Survival Reveal Potential ‘Supertargets’: Focus on Transcription
SIMPLE SUMMARY: A variety of anticancer therapeutic targets have been identified over the decades. Nevertheless, the complexity of biological regulation dictates the necessity of knowledge about mechanisms specific to a particular tumor type. Using the DepMap CRISPR/Cas9 knockout database, we perfor...
Autores principales: | Chetverina, Darya, Vorobyeva, Nadezhda E., Gyorffy, Balazs, Shtil, Alexander A., Erokhin, Maksim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252933/ https://www.ncbi.nlm.nih.gov/pubmed/37297004 http://dx.doi.org/10.3390/cancers15113042 |
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