Cargando…
The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway
Previous studies from our lab demonstrated that the crosstalk between brain-metastasizing melanoma cells and microglia, the macrophage-like cells of the central nervous system, fuels progression to metastasis. In the present study, an in-depth investigation of melanoma-microglia interactions elucida...
Autores principales: | Izraely, Sivan, Ben-Menachem, Shlomit, Malka, Sapir, Sagi-Assif, Orit, Bustos, Matias A., Adir, Orit, Meshel, Tsipi, Chelladurai, Maharrish, Ryu, Suyeon, Ramos, Romela I., Pasmanik-Chor, Metsada, Hoon, Dave S. B., Witz, Isaac P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253015/ https://www.ncbi.nlm.nih.gov/pubmed/37296634 http://dx.doi.org/10.3390/cells12111513 |
Ejemplares similares
-
Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression
por: Adir, Orit, et al.
Publicado: (2023) -
The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells – a case of inter‐tumor heterogeneity
por: Izraely, Sivan, et al.
Publicado: (2020) -
Inter-Tumor Heterogeneity—Melanomas Respond Differently to GM-CSF-Mediated Activation
por: Moshe, Adi, et al.
Publicado: (2020) -
ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis
por: Izraely, Sivan, et al.
Publicado: (2017) -
Cystatin C takes part in melanoma-microglia cross-talk: possible implications for brain metastasis
por: Moshe, Adi, et al.
Publicado: (2018)