Cargando…

Multi-Drug Cocktail Therapy Improves Survival and Neurological Function after Asphyxial Cardiac Arrest in Rodents

Background: Cardiac arrest (CA) can lead to neuronal degeneration and death through various pathways, including oxidative, inflammatory, and metabolic stress. However, current neuroprotective drug therapies will typically target only one of these pathways, and most single drug attempts to correct th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choudhary, Rishabh C., Shoaib, Muhammad, Hayashida, Kei, Yin, Tai, Miyara, Santiago J., d’Abramo, Cristina, Heuser, William G., Shinozaki, Koichiro, Kim, Nancy, Takegawa, Ryosuke, Nishikimi, Mitsuaki, Li, Timmy, Owens, Casey, Molmenti, Ernesto P., He, Mingzhu, Vanpatten, Sonya, Al-Abed, Yousef, Kim, Junhwan, Becker, Lance B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253071/ https://www.ncbi.nlm.nih.gov/pubmed/37296668 http://dx.doi.org/10.3390/cells12111548

Ejemplares similares

Mitochondrial transplantation therapy for ischemia reperfusion injury: a systematic review of animal and human studies
por: Hayashida, Kei, et al.
Publicado: (2021)

Pharmacological Approach for Neuroprotection After Cardiac Arrest—A Narrative Review of Current Therapies and Future Neuroprotective Cocktail
por: Choudhary, Rishabh C., et al.
Publicado: (2021)

The evaluation of pituitary damage associated with cardiac arrest: An experimental rodent model
por: Okuma, Yu, et al.
Publicado: (2021)

Exogenous mitochondrial transplantation improves survival and neurological outcomes after resuscitation from cardiac arrest
por: Hayashida, Kei, et al.
Publicado: (2023)

Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats
por: Yin, Tai, et al.
Publicado: (2021)

Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival
por: Choudhary, Rishabh C., et al.
Publicado: (2022)

Inhaled Gases as Therapies for Post–Cardiac Arrest Syndrome: A Narrative Review of Recent Developments
por: Hayashida, Kei, et al.
Publicado: (2021)

Real-Time Brain Monitoring by Near-Infrared Spectroscopy Predicts Neurological Outcome after Cardiac Arrest and Resuscitation in Rats: A Proof of Concept Study of a Novel Prognostic Measure after Cardiac Arrest
por: Takegawa, Ryosuke, et al.
Publicado: (2021)

Plasma metabolomics supports the use of long-duration cardiac arrest rodent model to study human disease by demonstrating similar metabolic alterations
por: Shoaib, Muhammad, et al.
Publicado: (2020)

Effects of Post‐Resuscitation Normoxic Therapy on Oxygen‐Sensitive Oxidative Stress in a Rat Model of Cardiac Arrest
por: Okuma, Yu, et al.
Publicado: (2021)

Intubated COVID-19 predictive (ICOP) score for early mortality after intubation in patients with COVID-19
por: Nishikimi, Mitsuaki, et al.
Publicado: (2021)

Challenges and Inconsistencies in Using Lysophosphatidic Acid as a Biomarker for Ovarian Cancer
por: Yagi, Tsukasa, et al.
Publicado: (2019)

Pneumatosis Intestinalis in the Setting of COVID-19: A Single Center Case Series From New York
por: Miyara, Santiago J., et al.
Publicado: (2021)

A method for measuring the molecular ratio of inhalation to exhalation and effect of inspired oxygen levels on oxygen consumption
por: Shinozaki, Koichiro, et al.
Publicado: (2021)

Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products
por: Shoaib, Muhammad, et al.
Publicado: (2021)

Near-Infrared Spectroscopy Assessments of Regional Cerebral Oxygen Saturation for the Prediction of Clinical Outcomes in Patients With Cardiac Arrest: A Review of Clinical Impact, Evolution, and Future Directions
por: Takegawa, Ryosuke, et al.
Publicado: (2020)

Mortality of Mechanically Ventilated COVID-19 Patients in Traditional versus Expanded Intensive Care Units in New York
por: Nishikimi, Mitsuaki, et al.
Publicado: (2022)

Bio-physiological susceptibility of the brain, heart, and lungs to systemic ischemia reperfusion and hyperoxia-induced injury in post-cardiac arrest rats
por: Aoki, Tomoaki, et al.
Publicado: (2023)

Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics
por: VanPatten, Sonya, et al.
Publicado: (2020)

Reply: COVID-19 Mortality Differences: Patient-related Data and Intensive Care Unit Load Are Prerequisites
por: Nishikimi, Mitsuaki, et al.
Publicado: (2022)

Bilateral Spontaneous Pneumothorax in a COVID-19 and HIV-Positive Patient: A Case Report
por: Cho, Young Min, et al.
Publicado: (2021)

SARS-CoV-2 and interferon blockade
por: Diamond, Betty, et al.
Publicado: (2020)

Brain monitoring using near-infrared spectroscopy to predict outcome after cardiac arrest: a novel phenotype in a rat model of cardiac arrest
por: Takegawa, Ryosuke, et al.
Publicado: (2021)

Comparison of point-of-care peripheral perfusion assessment using pulse oximetry sensor with manual capillary refill time: clinical pilot study in the emergency department
por: Shinozaki, Koichiro, et al.
Publicado: (2019)

Relative Ratios Enhance the Diagnostic Power of Phospholipids in Distinguishing Benign and Cancerous Ovarian Masses
por: Yagi, Tsukasa, et al.
Publicado: (2019)

Does training level affect the accuracy of visual assessment of capillary refill time?
por: Shinozaki, Koichiro, et al.
Publicado: (2019)

Asphyxiated by a Tooth
por: Miller, N.
Publicado: (1882)

Restoration of an Asphyxiated Infant
Publicado: (1881)

Tissue‐Specific Metabolic Profiles After Prolonged Cardiac Arrest Reveal Brain Metabolome Dysfunction Predominantly After Resuscitation
por: Choi, Jaewoo, et al.
Publicado: (2019)

Continuous and repeat metabolic measurements compared between post-cardiothoracic surgery and critical care patients
por: Shinozaki, Koichiro, et al.
Publicado: (2023)

The mechanisms and treatment of asphyxial encephalopathy
por: Wassink, Guido, et al.
Publicado: (2014)

Asphyxiation with a Fentanyl Patch
por: Mansfield, Aaron S., et al.
Publicado: (2013)

Placental Transfusion for Asphyxiated Infants
por: Katheria, Anup C., et al.
Publicado: (2019)

Prophylaxis against Asphyxiating Gases
Publicado: (1916)

The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID-19
por: D’Abramo, Flavio
Publicado: (2021)

DHA-supplemented diet increases the survival of rats following asphyxia-induced cardiac arrest and cardiopulmonary bypass resuscitation
por: Kim, Junhwan, et al.
Publicado: (2016)

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models
por: Ahmed, Mohamed, et al.
Publicado: (2016)

Lethal Injection for Execution: Chemical Asphyxiation?
por: Zimmers, Teresa A, et al.
Publicado: (2007)

Bilateral correction of asphyxiating thoracic dystrophy
por: Wang, Wenlin, et al.
Publicado: (2022)

Intoxication by Asphyxiating Gas and Its Treatment
Publicado: (1918)

Cannot write session to /tmp/vufind_sessions/sess_2h4akturfhlvb6cfq66hcra79p