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Degranulation of Mast Cells as a Target for Drug Development

Mast cells act as key effector cells of inflammatory responses through degranulation. Mast cell degranulation is induced by the activation of cell surface receptors, such as FcεRI, MRGPRX2/B2, and P2RX7. Each receptor, except FcεRI, varies in its expression pattern depending on the tissue, which con...

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Detalles Bibliográficos
Autores principales: Yang, Bo-Gie, Kim, A-Ram, Lee, Dajeong, An, Seong Beom, Shim, Yaein Amy, Jang, Myoung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253146/
https://www.ncbi.nlm.nih.gov/pubmed/37296626
http://dx.doi.org/10.3390/cells12111506